Esther Dyson is chairman of EDventure Holdings and founder of, for Health Intervention Coordinating Council. HICCup is an open-source initiative devoted to defining and testing a business model for investing in health (not health care) that will return profits to investors and health to the participants. From October 2008 to March 2009, she lived in Star City outside Moscow, training as a backup cosmonaut. She will deliver a talk entitled “Data, Predictions, and Luck: The Implications of Knowing Almost Everything.”